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14-3-3E (YWHAE)
英文名:Rabbit Monoclonal Antibody
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检测信息查询
货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
1308113291-100ul | 现货 | 0 | ¥0 | 请登录 |
别 名 | YWHAE antibody, 14-3-3E antibody, FLJ45465 antibody, FLJ53559 antibody, KCIP-1 antibody, MDCR antibody, MDS antibody, 14-3-3 protein epsilon antibody, antibody |
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产品参数 | 【产品介绍】The 14-3-3 epsilon protein (14-3-3E) is one
of seven isoforms in the 14-3-3 protein family, which consists of acidic proteins expressed at high levels in neurons of the central nervous system (1). It is an adaptor protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. 14-3-3E binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif (2). It also interacts with both insulin-like growth factor I receptor (IGFIR) and insulin receptor substrate I (IRS-1), suggesting its role in the regulation of insulin sensitivity (3). 14-3-3E has also been implicated in the pathogenesis of small cell lung cancer (4). Recommended Applications WB, ICC, FC Applications and Recommended Dilution Factors WB: 1:1,000 - 10,000 ICC: 1:100 - 250 FC: 1:10 - 100 Species Reactivity Human, Mouse, Rat Specificity A synthetic peptide corresponding to residues in human 14-3-3E was used as an immunogen. |
性状 | 【反应特异性】Human , Mouse , Rat
【克隆 ID】EPR3919 【用途】WB , ICC , FC 【抗原分子量】28kDa |
贮存 | Storage Condition and Buffer Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |