ABCD1 (mouse) (Ccl22)

英文名:Rabbit Monoclonal Antibody
Cas号:
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别 名 Ccl22 antibody, ABCD-1 antibody, DCBCK antibody, MDC antibody, Scya22 antibody, C-C motif chemokine 22 antibody, Activated B and dendritic cell-derived antibody, CC chemokine ABCD-1 antibody, Small-inducible cytokine A22 antibody
Cas号
M D L
分子式
分子量
产品参数 【产品介绍】Chemokines are a large family of small
secreted proteins that regulate migration of white
blood cells. Based on the arrangement of the first two
of the four conserved cysteine residues, chemokines
are classified into four subfamilies, CXC, CC, C
and recently identified CX3C (1). The CC chemokines,
in which the first 2 cysteines are adjacent, usually act
on monocytes, T lymphocytes, and, in some cases, eosinophils, basophils, or mast cells. The CC
subfamily proteins are 70 to 100 amino acids long, have
25 to 75% identity with each other, and include novel
member of the CC chemokine subfamily, designated
ABCD1 (SCYA22). The ABCD1 shares 28 to 34% identity
with other CC chemokines and contains the
characteristic 4-cysteine motif and 9 other highly
conserved residues (2). The activated T cell-attracting
CC chemokine CCL22 is expressed by stimulated B cells
and mature dendritic cells (DC). Both identical
and distinct proteins contribute to expression of CCL22
in DC and B cells (3).


Recommended Applications

WB, IHC
Applications and Recommended Dilution Factors

WB: 1:1,000 - 10,000 (5 ng)
IHC: 1:100 - 250
Species Reactivity *

Mouse

*Species cross-reactivity is based on WB analysis.

Specificity

A synthetic peptide corresponding to residues in mouse
ABCD1 was used as an immunogen.
性状 【反应特异性】Mouse
【克隆 ID】EPR1362
【用途】WB , IHC
【抗原分子量】8kDa
贮存 Storage Condition and Buffer Store at -20 °C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt
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