|
|
|
| 生化科研试剂 >> 抗体产品 >> 一抗 |
| |
Ape 1 (APEX1)
Rabbit Monoclonal Antibody |
| 别 名： |
APEX1 antibody, APE antibody,
APE1 antibody, APEN antibody,
APEX antibody, APX antibody,
HAP1 antibody, REF1
antibody, DNA-(apurinic or
apyrimidinic site) lyase,
mitochondrial antibody, REF-1
antibody, Redox factor-1 antibody |
| 货号 |
品名 |
规格 |
包装 |
单价 |
货期 |
库存 |
| 1227177533 |
Ape 1 (APEX1) |
|
100ul |
询价 |
现货 |
3天 |
| 提示信息：偏远地区如新疆西藏宁夏甘肃等地可能无法运送液体，下单前请联系客服。 |
| 性 状： |
【反应特异性】Human , Mouse , Rat
【克隆 ID】EPR4022
【用途】WB , IHC
【抗原分子量】36kDa |
| 质量标准： |
【产品介绍】Apurinic endonuclease (Ape 1) functions as
a major DNA repair enzyme that is essential
for embryogenesis and cell viability (1). It is involved
in the base excision repair (BER) pathway and acts as
a reduction-oxidation signaling factor to
maintain transcription factors in an active reduced
state (2). Ape 1 plays a critical role as a
transcriptional coactivator for different
transcription factors (i.e. AP-1, NF-kappaB, p53)
in controlling different cellular processes such
as apoptosis, proliferation, and differentiation
(3). Elevated levels of Ape 1 have been found in
cancers such as ovarian, cervical, and prostate (4).
Recommended Applications
WB, IHC
Applications and Recommended Dilution Factors WB: 1:10,000-50,000
IHC: 1 : 100 - 250
Species Reactivity * Human, Mouse, Rat *Mouse cross reactivity tested by western blot and
IHC Rat cross reactivity tested by western blot only Products Data
Western blot analysis on (A) K562, (B) HepG2, and (C)
Raji cell lysates using anti-Ape 1 RabMAb (cat. #2851-1). Immunohistochemical analysis of paraffin-embedded
human tonsil tissue using anti-Ape 1 RabMAb (cat. #2851-1). Immunohistochemical analysis of paraffin-embedded
human kidney tissue using anti-Ape 1RabMAb (cat. #2851-1). Specificity A synthetic peptide corresponding to residues near
the N-terminus in human Ape 1 was used as an immunogen. |
| 贮 存： |
Storage Condition and Buffer Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4),
0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and
0.05% BSA. Stable for 12 months from date of receipt. |
|
沪公网安备 31012002003054号
