【产品介绍】BMP11 is a member of the bone
morphogenetic protein (BMP) family and the
TGF-beta superfamily. This group of proteins
is characterized by a polybasic proteolytic processing
site, which is cleaved to produce a mature
protein containing seven conserved cysteine residues.
The members of this family are regulators of cell growth
and differentiation in both embryonic and adult
tissues. Studies in mice and Xenopus suggest that BMP11
is involved in mesodermal formation and neurogenesis
during embryonic development (1).
Recommended Applications
WB, IHC
Applications and Recommended Dilution Factors WB: 1:1,000 - 10,000
IHC: 1:500 - 1000
Species Reactivity * Human, Mouse, Rat *Species cross-reactivity is based on WB analysis. Products Data Western blot analysis on (A) HeLa and (B) human
heart lysates using anti-BMP11 RabMAb (cat. #5177-1). Immunohistochemical analysis of paraffin-embedded
human colon adenocarcinoma tissue using anti-BMP11
RabMAb (cat. #5177-1). Specificity A synthetic peptide corresponding to residues in human
BMP11 was used as an immunogen. |
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