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CD51 / Integrin alpha-V (ITGAV)
英文名：Rabbit Monoclonal Antibody
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检测信息查询
| 货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
| 1308113431-100ul | 现货 | 0 | ￥0 | 请登录 |
| 别 名 | ITGAV antibody, CD51 antibody, DKFZp686A08142 antibody, MSK8 antibody, VNRA antibody, Integrin alpha-V light chain antibody, Vitronectin receptor subunit alpha antibody |
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| 产品参数 | 【产品介绍】Integrins are heterodimeric integral
membrane proteins composed of an alpha chain and a beta chain. The I-domain containing CD51 / Integrin alpha-V undergoes post-translational cleavage to yield disulfide-linked heavy chain (125 kDa) and light chain (25 kDa), which combine with multiple integrin beta chains to form different integrins. Among the known associating beta chains (beta chains 1,3,5,6, and 8; ITGB1, ITGB3, ITGB5, ITGB6, and ITGB8), each can interact with extracellular matrix ligands; the CD51 / Integrin alpha-V, perhaps the most studied of these, is referred to as the Vitronectin receptor (VNR). In addition to adhesion, many integrins are known to facilitate signal transduction (1). Recommended Applications WB, FC Applications and Recommended Dilution Factors WB: 1:1,000 - 10,000 FC: 1:10 - 100 Species Reactivity * Human, Mouse, Rat *Species cross-reactivity is based on WB analysis Products Data Western blot analysis on (A) A549, (B) A431, (C) C6, (D) RAW264.7, (E) PC-12, and (F) NIH/3T3 cell lysates using anti-CD51 / Integrin alpha-V RabMAb (cat. #3919-1). Flow cytometric analysis of permeabilized A549 cells using anti-CD51 / Integrin alpha-V RabMAb (red) (catalog # 3919-1) or a rabbit IgG (negative) (green). Specificity A synthetic peptide corresponding to residues in the intracellular domain of human CD51 / Integrin alpha-V was used as an immunogen. |
| 性状 | 【反应特异性】Human , Mouse , Rat
【克隆 ID】EPR5583 【用途】WB , FC 【抗原分子量】150/25kDa |
| 贮存 | Storage Condition and Buffer Store at -20 °C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt |
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