eIF-3B (EIF3B)

英文名:Rabbit Monoclonal Antibody
Cas号:
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别 名 EIF3B antibody, EIF3-ETA antibody, EIF3-P110 antibody, EIF3-P116 antibody, EIF3S9 antibody, MGC104664 antibody, MGC131875 antibody, PRT1 antibody, Eukaryotic translation initiation factor 3 subunit B antibody, eIF-3-eta antibody, eIF3 p110 antibody, eIF3
Cas号
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分子式
分子量
产品参数 【产品介绍】eIF-3B is a component of the
eukaryotic translation initiation factor 3 (eIF-3)
complex, which is required for several steps in
the initiation of protein synthesis. The eIF-3
complex associates with the 40S ribosome and facilitates
the recruitment of eIF-1, eIF-1A, eIF-2:GTP:
methionyl-tRNAi and eIF-5 to form the 43S
preinitiation complex (43S PIC). The eIF-3 complex is
also required for disassembly and recycling
of posttermination ribosomal complexes and
subsequently prevents premature joining of the 40S and
60S ribosomal subunits prior to initiation (1).


Recommended Applications

WB, ICC, IP, FC
Applications and Recommended Dilution Factors

WB: 1:10,000 - 50,000
ICC: 1:100 - 250
IP: 1:10 - 100
FC: 1:10 - 100
Species Reactivity *

Human, Mouse, Rat

*Species cross-reactivity is based on WB analysis.

Products Data

Western blot analysis on (A) A431, (B) 293T, (C) Jurkat,
(D) HeLa, and (E) Caco-2 cell lysates using
anti-eIF-3B RabMAb (cat. #5423-1).

Flow cytometric analysis of permeabilized HeLa cells
using anti-eIF-3B RabMAb (red) (catalog # 5423-1) or
a rabbit IgG (negative) (green).

Specificity

A synthetic peptide corresponding to residues in
human eIF-3B was used as an immunogen.
性状 【反应特异性】Human , Mouse , Rat
【克隆 ID】EPR5804
【用途】WB , ICC , FC , IP
【抗原分子量】116kDa
贮存 Storage Condition and Buffer Store at -20° C. Buffer: PBS (pH 7.2), 50% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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