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Ezrin Rabbit Antibody
英文名：Rabbit Monoclonal IgG
Cas号：
Cas号：
检测信息查询
| 货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
| 1308113566-100ul | 现货 | 0 | ￥0 | 请登录 |
| 别 名 | p81, Cytovillin, Villin-2 |
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| 产品参数 | 【产品介绍】Erzin, a member of the Ezrin, Radixin,
Moesin (ERM) family, is a linker protein located between cell surface recept o r s, adhesion molecules, a n d actin cytoskeleton (1-2). Ezrin activity is regulated by intramolecular interactions between N- a n d C-terminal ERM association domains (3). Erzin tyrosine phosph o r ylation can also be induced by EGF, PDGF a n d HGF stimulation. Erzin interacts with PI3-K protein kinase A a n d Rho (4). In response to epidermal growth fact o r (EGF) the microvillar c o r e protein ezrin is phosph o r ylated transiently to a high level on tyrosine residues in human epidermoid carcinoma A431 cells. Tyr145, lies in the N-terminal region of homology that is common to the b a n d 4.1-talin-ezrin protein family. This tyrosine residue a n d its vicinal amino acids are conserved throughout the family members, including radixin, moesin, a n d the two phosphotyrosine phosphatases, PTP H1 a n d PTP MEG, but not in b a n d 4.1 o r talin (5). WB: 1:1000 - 5000 ICC: 1:100 – 250 Flow Cytometry: 1:20 A. Western blot analysis on (A) 293, (B) A431 a n d (C) SH-SY5Y cell lysate using anti-Ezrin RabMAb (cat. # 2255-1), dilution 1:10,000. |
| 性状 | 【反应特异性】Human , Mouse , Rat
【克隆 ID】EP924Y 【用途】WB , ICC , FC 【抗原分子量】81 kDa |
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