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Fes (FES)
英文名：Rabbit Monoclonal Antibody
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检测信息查询
| 货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
| 1308113583-100ul | 现货 | 0 | ￥0 | 请登录 |
| 别 名 | FES antibody, FPS antibody, Tyrosine-protein kinase Fes/Fps antibody, Proto-oncogene c-Fes antibody, Proto-oncogene c-Fps antibody |
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| 产品参数 | 【产品介绍】Fes (c-Fes) is a non-receptor protein-
tyrosine kinase implicated in myeloid, vascular endothelial and neuronal cell differentiation. Closely related to Fer, Fes is characterized by a unique amino-terminal region (critical for kinase regulation and downstream signaling), a central SH2 domain, and a carboxyl-terminal kinase domain (1, 2). Fes lacks an SH3 domain, a negative regulatory tail, and other features that contribute to negative regulation of c-Src, c-Abl, and other cytoplasmic tyrosine kinases. Fes activation in response to growth factors and cytokines has been linked to various cellular events including survival, proliferation, differentiation, and reorganization of the cytoskeleton. Fes has been implicated as a tumor suppressor in colorectal cancer (3). Recommended Applications WB, ICC Applications and Recommended Dilution Factors WB: 1:1,000 - 5,000 ICC: 1:50 - 100 Species Reactivity * Human, Mouse *Cross reactivity determined by western blot only. Products Data Western blot analysis on A) TF-1, B) fetal kidney, and C) U937 lysates using anti-Fes RabMAb (cat. #2720-1). Specificity A synthetic peptide corresponding to residues near the N-terminus of human Fes was used as an immunogen. |
| 性状 | 【反应特异性】Human , Mouse
【克隆 ID】EPR3229 【用途】WB , ICC 【抗原分子量】93kDa |
| 贮存 | Storage Condition and Buffer Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
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