GFAP (N-term)

英文名:Rabbit Monoclonal Antibody
Cas号:
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别 名 GFAP antibody, FLJ45472 antibody, Glial fibrillary acidic protein antibody, antibody
Cas号
M D L
分子式
分子量
产品参数 【产品介绍】Glial fibrillary acidic protein (GFAP)
belongs to the class III of the intermediate filament
(IF) proteins highly specific to astrocytes which
function as nerve cells in the brain and in the
central nervous system (CNS) (1-2). Two other class III
IF proteins, nestin and vimentin, dominate in
immature astrocytes, while GFAP is most abundant in
mature astrocytes (3). GFAP is used as a marker
to distinguish astrocytes form other glial cells
during development. Mutations in GFAP cause
Alexander disease, a rare disorder of the CNS. Most
frequent mutations are located at Arginine 79 or 239 (4).


Recommended Applications

WB, IHC, ICC, IP
Applications and Recommended Dilution Factors

WB: 1:1,000 - 10,000
IHC: 1:250
ICC: 1:100
IP: 1:40
Species Reactivity *

Human, Mouse, Rat

*Mouse cross reactivity tested by western blot and IHC
Rat cross reactivity tested by western blot only

Products Data

A. Western blot analysis on (A) human brain lysate and
(B) rat brain lysate using anti-GFAP RabMAb
(cat. # 2301-1).

B. Immunohistochemical analysis of paraffin-embedded
human brain using anti-GFAP RabMAb. (cat #2301-1)

C. Immunohistochemical analysis of paraffin-embedded
human glioma using anti-GFAP RabMAb (cat #2301-1)

Specificity

A synthetic peptide corresponding to residues in the
N-term of human GFAP was used as immunogen.
性状 【反应特异性】Human , Mouse , Rat
【克隆 ID】EPR1034Y
【用途】WB , IHC , ICC , IP
【抗原分子量】50kDa
贮存 Storage Condition and Buffer Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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