HNF4 Alpha DyLight® 488

英文名:HNF4A
Cas号:
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别 名 HNF4A antibody, FLJ39654 antibody, HNF4 antibody, HNF4a7 antibody, HNF4a8 antibody, HNF4a9 antibody, HNF4alpha antibody, MODY antibody, MODY1 antibody, NR2A1 antibody, NR2A21 antibody, TCF antibody, TCF14 antibody, Hepatocyte nuclear factor 4-alpha antibo
Cas号
M D L
分子式
分子量
产品参数 【产品介绍】HNF4 (Hepatocyte Nuclear Factor 4) is a
nuclear receptor protein belonging to the steroid
hormone receptor superfamily. HNF4 is commonly expressed
in the liver and plays a critical role in liver
development by establishing and maintaining
hepatocyte differentiation (1). In human, two isoforms
of HNF4 exists, alpha and gamma. HNF4 alpha
is transcriptionally controlled transcription factor,
which binds to DNA sites required for the transcription
of alpha 1- antitrypsin, Apo CIII, transthyretin genes,
and HNF1 alpha (2). HNF4 alpha interacts with PGC-1
to activate gluconeogenesis, leading to
lipoprotein metabolism regulation (3). HNF4 alpha
defects are known to cause type I diabetes (4).

Recommended Applications
ICC
Applications and Recommended Dilution Factors
ICC: 1:50 - 100
Species Reactivity
Human

Products Data

Immunofluorescent staining of HepG2 cells using
anti-HNF-4 antibody conjugated with Dylight 488
(green, Cat# 4580-1) and Dapi (blue).

Specificity
A synthetic peptide corresponding to residues in human
HNF4 was used as an immunogen.
性状 【产品类型】Rabbit Monoclonal Antibody
【反应特异性】Human
【克隆 ID】EPR3648
【用途】ICC
【产品性状】
【阳性对照】
【产品浓度】
【细胞定位】
【抗原分子量】52kDa
贮存 Store at 2-8° C. PBS (pH 7.2), 0.02% sodium azide, 0.05% BSA. Protect from light. Stable for 6 months from date of receipt.
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