IGF-2R

英文名:IGF2R
Cas号:
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别 名 IGF2R antibody, CD222 antibody, CIMPR antibody, M6P-R antibody, MPR1 antibody, MPRI antibody, Cation-independent mannose-6-phosphate receptor antibody, M6P/IGF2 receptor antibody
Cas号
M D L
分子式
分子量
产品参数 【产品介绍】IGF-2R is a receptor for both insulin-
like growth factor 2 (IGF-2) and mannose 6-phosphate
(M6P). The IGF-2 and M6P binding sites are located
on different segments of the receptor. This
receptor functions in the intracellular trafficking
of lysosomal enzymes, activation of transforming
growth factor beta, and degradation of IGF-2. While
mouse IGF-2R shows exclusive expression from the
maternal allele, imprinting of human IGF-2R appears to
be polymorphic, with only a minority of individuals
showing expression from the maternal allele (1).

Recommended Applications
WB, IHC, ICC, IP, FC
Applications and Recommended Dilution Factors
WB: 1:50,000 - 200,000
IHC: 1:250 - 500
ICC: 1:100 - 250
IP: 1:10 - 100
FC: 1:100 - 500
Species Reactivity *
Human, Mouse, Rat
*Species cross-reactivity is based on WB analysis.

Products Data

Western blot analysis on (A) Jurkat, (B) 293T, and
(C) Caco-2 cell lysates using anti-IGF-2R RabMAb
(cat. #5230-1).

Immunohistochemical analysis of paraffin-embedded
papillary carcinoma tissue using anti- IGF-2R RabMAb
(cat. #5230-1).

Immunohistochemical analysis of paraffin-embedded
human tonsil tissue using anti- IGF-2R RabMAb (cat. #5230-1).

Immunofluorescent staining of 293T cells using
anti-IGF-2R RabMAb (cat. #5230-1).

Specificity
A synthetic peptide corresponding to residues on
the C-terminus of human IGF-2R was used as an immunogen.
性状 【产品类型】Rabbit Monoclonal Antibody
【反应特异性】Human , Mouse , Rat
【克隆 ID】EPR6599
【用途】WB , IHC , ICC , FC , IP
【产品性状】
【阳性对照】
【产品浓度】
【细胞定位】
【抗原分子量】300kDa
贮存 Store at -20 °C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt
本网站销售的所有产品仅用于工业应用或者科学研究等非医疗目的,不可用于人类或动物的临床诊断或者治疗,非药用,非食用。
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