Ki-67 (MKI67)

英文名:Ki-67 (MKI67)
Cas号:
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别 名 MKI67 antibody, KIA antibody, Antigen KI-67 antibody, antibody
Cas号
M D L
分子式
分子量
产品参数 【产品介绍】Ki-67 antigen is a nuclear antigen
specifically associated with cell proliferation. Ki-67
is expressed in all proliferating cells which are in
the active phases of the cell cycle (late G1, S, G2,
and mitosis), but absent in resting cells. In G1, it
is predominately localized in the perinucleolar region
and also found in nuclear matrix in the later phases
(1). Ki-67 is thought to be involved in the maintaining
of cell proliferation, however, its exact mechanism
for function is unknown. Due to the fact that Ki-67 can
be used to determine the growth fraction (the proportion
of the cells committed to the cell cycle), it is consider
an important marker in human tumor diagnostics
and prognostics (2).

Recommended Applications
WB, IHC, ICC, FC
Applications and Recommended Dilution Factors
WB: 1:500 - 1,000
IHC: 1:500 - 1,000
ICC: 1:250 - 500
FC: 1:550
Species Reactivity
Human

Products Data

Western blot analysis on HeLa lysates using
anti-Ki-67 RabMAb (cat. #2746-1).

Immunohistochemical analysis of paraffin-embedded
human tonsil using anti-Ki-67 RabMAb (cat. #2746-1).

Immunohistochemical analysis of paraffin-embedded
human colonic adenocarcinoma using anti-Ki-67 RabMAb
(cat. #2746-1).

Immunofluorescent staining of HeLa cells using
anti-Ki-67 RabMAb (cat. #2746-1).

Specificity
A synthetic peptide corresponding to residues in human
Ki-67 was used as an immunogen.
性状 【产品类型】Rabbit Monoclonal Antibody
【反应特异性】Human
【克隆 ID】EPR3610
【用途】WB , IHC , ICC , FC
【产品性状】
【阳性对照】
【产品浓度】
【细胞定位】
【抗原分子量】395kDa
贮存 Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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