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Kv4.2
英文名：Kv4.2
Cas号：
Cas号：
检测信息查询
| 货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
| 1308114484-100ul | 现货 | 0 | ￥0 | 请登录 |
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| 产品参数 | 【产品介绍】Kv4.2, a voltage-gated K+ (Kv) channel
subunit, has been suggested to be the key component of the subthreshold A-type K+ currents (I(SA)s) rec o r ded from the specific subcellular compartments of certain CNS neurons (1). A-type channels, encoded by the p o r e-f o r ming alpha-subunits of the Kv4.x family, are particularly imp o r tant in regulating membrane excitability in the CNS a n d the heart. Kv4.2 is a Shal-type potassium channel that passes an A-type current a n d is localized to dendrites a n d cell bodies in the hippocampus (2). Deletion of the Kv4.2 gene a n d a loss of Kv4.2 protein resulted in a specific a n d near-complete elimination of A-type K+ currents from the apical dendrites of CA1 pyramidal neurons. The absence of dendritic Kv4.2-encoded A-type K+ currents led to an increase of bAP amplitude a n d an increase of concurrent Ca2+ influx (3). WB: 1:1000 IHC: 1:100 250 Flow Cytometry: 1:30 A. Western blot analysis on human brain lysate using anti-Kv4.2 RabMAb (cat. # 1834-1), dilution 1:1000 B. Immunohistochemical staining of paraffin-embedded human brain using anti-Kv4.2 RabMAb (cat. # 1834-1). |
| 性状 | 【产品类型】Rabbit Monoclonal IgG
【反应特异性】Human 【克隆 ID】EP982Y 【用途】WB , IHC , FC 【产品性状】 【阳性对照】 【产品浓度】 【细胞定位】 【抗原分子量】80 kDa |
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