LI-Cadherin (CDH17)

英文名:LI-Cadherin (CDH17)
Cas号:
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别 名 CDH17 antibody, CDH16 antibody, FLJ26931 antibody, HPT-1 antibody, HPT1 antibody, MGC138218 antibody, MGC142024 antibody, Cadherin-17 antibody, Intestinal peptide-associated transporter HPT-1 antibody, Liver-intestine cadherin antibody
Cas号
M D L
分子式
分子量
产品参数 【产品介绍】Cadherins are transmembrane glycoproteins
that mediate calcium-dependent cell adhesion.
LI-cadherin (liver-intestine cadherin), also known
as cadherin-17, may play a role in the
morphological organization of the liver and intestine
(1). Thus, it is involved in intestinal peptide
transport (1). LI-cadherin contains seven cadherin
repeats and a short cytoplasmic domain that does
not interact with catenins or the actin cytoskeleton (2).
It is expressed in intestinal epithelial cells in
the gastrointestinal tract, as well as the pancreatic
duct (1, 2). Within the human intestinal mucosa,
LI-cadherin is specifically concentrated in the
lateral domain of the plasma membrane residing
between adjacent enterocytes but spared from
adherens junctions (3).

Recommended Applications
WB, IHC, IP
Applications and Recommended Dilution Factors
WB: 1:1,000-10,000
IHC: 1:250 - 500
IP: 1:10 - 100
Species Reactivity
Human
Products Data

Western blot analysis on (A) human small intestine,
(B) colon cancer, and (C) HT-29 cell lysates using
anti-LI-cadherin RabMAb (cat. # 2930-1).

Immunohistochemical staining of paraffin-embedded
human colon tissue using anti-LI-cadherin RabMAb
(cat. #2930-1).

Immunohistochemical staining of paraffin-embedded
human colonic adenocarcinoma tissue using
anti-LI-cadherin RabMAb (cat. #2930-1).

Specificity
A synthetic peptide corresponding to residues in
human LI-cadherin was used as an immunogen.

性状 【产品类型】Rabbit Monoclonal Antibody
【反应特异性】Human
【克隆 ID】EPR3996
【用途】WB , IHC , IP
【产品性状】
【阳性对照】
【产品浓度】
【细胞定位】
【抗原分子量】120kDa
贮存 Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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