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Recombinant Mouse Acidic Fibroblast Growth Factor

英文名：
Cas号：
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别 名
Cas号
M D L
分子式
分子量
产品参数
性状 Recombinant Mouse Acidic Fibroblast Growth Factor是由FGF1基因编码的生长因子和信号蛋白。
Synonyms
rMuaFGF; HBGF-1; FGF1; FGF-a; FGF-acidic
Species
Mouse

Source
E. coli

Accession
P61148

Gene ID
14164

Molecular Weight
Approximately 15.8 kDa

AA Sequence
FNLPLGNYKK PKLLYCSNGG HFLRILPDGT VDGTRDRSDQ HIQLQLSAES AGEVYIKGTE TGQYLAMDTE GLLYGSQTPN EECLFLERLE ENHYNTYTSK KHAEKNWFVG LKKNGSCKRG PRTHYGQKAI LFLPLPVSSD

Biological Activity
The ED50 is <0.4 ng/mL as measured by 3T3 cells, corresponding to a specific activity of >2.5 × 106 units/mg.

Appearance
Lyophilized powder.

Formulation
Lyophilized after extensive dialysis against PBS.

Endotoxin Level
<0.2 EU/μg, determined by LAL method.

Reconstitution
Reconstitute the lyophilized recombinant Murine Acidic Fibroblast Growth Factor (rMuaFGF) to 100 µg/mL using ddH2O.

Storage & Stability
Lyophilized recombinant Murine Acidic Fibroblast Growth Factor (rMuaFGF) is stored at -20°C. After reconstitution, it is stable at 4°C for 2 weeks or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping
Room temperature in continental US; may vary elsewhere.

Background
Acidic Fibroblast Growth Factor is involved in a wide spectrum of biological functions including tissue development and repair, angiogenesis, proliferation of both epithelial and mesenchymal cells, and tumorigenesis. The biological activities of Acidic Fibroblast Growth Factor depend on binding to highly specific cell surface receptors, among which, fibroblast growth factor receptor 4 (FGFR4) is highly specific[1].
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