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Recombinant Human Cardiotrophin-1

英文名：
Cas号：
检测信息查询
货号 规格 货期 库存 价格 会员价 订购
1308132668-10 μg 0 ￥4800 请登录
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1308132668-50 μg 0 ￥13200 请登录
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别 名
Cas号
M D L
分子式
分子量
产品参数
性状 Recombinant Human Cardiotrophin-1 (CHO-expressed) 是IL-6细胞因子家族的一员，是能量稳态和糖脂代谢的关键调控因子。
Synonyms
rHuCT-1; CTF1 ; 重组人Cardiotrophin-1 (CHO细胞表达)
Species
Human

Source
CHO

Accession
Q16619

Gene ID
1489

Molecular Weight
24-26 kDa

AA Sequence
SRREGSLEDP QTDSSVSLLP HLEAKIRQTH SLAHLLTKYA EQLLQEYVQL QGDPFGLPSF SPPRLPVAGL SAPAPSHAGL PVHERLRLDA AALAALPPLL DAVCRRQAEL NPRAPRLLRR LEDAARQARA LGAAVEALLA ALGAANRGPR AEPPAATASA ASATGVFPAK VLGLRVCGLY REWLSRTEGD LGQLLPGGSA

Biological Activity
The ED50 is <0.4 ng/mL as measured by TF-1 cells.

Appearance
Lyophilized powder.

Formulation
Lyophilized after extensive dialysis against PBS.

Endotoxin Level
<0.2 EU/μg, determined by LAL method.

Reconstitution
Reconstitute the lyophilized recombinant Human Cardiotrophin-1 (CHO-expressed) (rHuCT-1) to 100 μg/mL using ddH2O or PBS.

Storage & Stability
Lyophilized recombinant Human Cardiotrophin-1 (CHO-expressed) (rHuCT-1) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping
Room temperature in continental US; may vary elsewhere.

Background
Cardiotrophin (CT)-1 belongs to the IL-6 family of cytokines[1]. Cardiotrophin-1 (CT1) plays an important role in the differentiation, development, and survival of neural stem cells. CT1 plays a key role in neural tissue development and has survival-promoting, anti-apoptotic effects in neural injury or death. CT1 induces a phenotypic switch in sympathetic neurons and promotes the survival of dopaminergic neurons from the central nervous system and ciliary neurons from the periphery[2].
贮存
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