1. 首页
  2. 生化科研试剂
  3. 蛋白质组化

Recombinant Mouse MCP-1/CCL2 (HEK293-expressed)

英文名：
Cas号：
检测信息查询
货号 规格 货期 库存 价格 会员价 订购
1308132747-10 μg 0 ￥3900 请登录
- +
1308132747-50 μg 0 ￥10400 请登录
- +
偏远地区如新疆西藏宁夏甘肃等地可能无法运送液体，下单前请联系客服。
别 名
Cas号
M D L
分子式
分子量
产品参数
性状 Recombinant Mouse MCP-1/CCL2 (HEK293-expressed) 是属于CC趋化因子家族的细胞因子。

Synonyms
rMuMCP-1/CCL2; C-C motif chemokine 2; MCAF; MCP-1; SCYA2 ; 重组小鼠MCP-1/CCL2 (HEK293-表达)
Species
Mouse

Source
HEK 293

Accession
P10148

Gene ID
20296

Molecular Weight
Approximately 8 kDa

AA Sequence
QPDAVNAPLT CCYSFTSKMI PMSRLESYKR ITSSRCPKEA VVFVTKLKRE VCADPKKEWV QTYIKNLDRN QMR

Biological Activity
The ED50 is <0.3 μg/mL as measured by CHO-K1/Gα15/mCCR2 cells (human Gα15 and mouse CCR2 stably expressed in CHO-K1 cells).

Appearance
Lyophilized powder.

Formulation
Lyophilized after extensive dialysis against PBS.

Endotoxin Level
<0.2 EU/μg, determined by LAL method.

Reconstitution
Reconstitute the lyophilized recombinant Mouse MCP-1/CCL2 (HEK293-expressed) (rMuMCP-1/CCL2) to 100 μg/mL using ddH2O or PBS.

Storage & Stability
Lyophilized recombinant Mouse MCP-1/CCL2 (HEK293-expressed) (rMuMCP-1/CCL2) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping
Room temperature in continental US; may vary elsewhere.

Background
CCL2 is produced by a variety of cell types, either constitutively or after induction by oxidative stress, cytokines, or growth factors. CCL2 is produced by many cell types, including endothelial, fibroblasts, epithelial, smooth muscle, mesangial, astrocytic, monocytic, and microglial cells. CCL2 regulates the migration and infiltration of monocytes, memory T lymphocytes, and natural killer (NK) cells[1]. The chemokine CCL2 and its main chemokine receptor CCR2 have been implicated in the pathogenesis of several different disease processes, including vascular permeability and attraction of immune cells during metastasis, a number of different neurological disorders, autoimmune disease, obesity, and atherosclerosis[2].
贮存
本网站销售的所有产品仅用于工业应用或者科学研究等非医疗目的，不可用于人类或动物的临床诊断或者治疗，非药用，非食用。
X
QQ