Recombinant Human Monocyte Chemotactic Protein-3/CCL7 (CHO-expressed) 是趋化因子和引诱剂,用于各种白细胞,包括单核细胞和嗜中性粒细胞。 Synonyms rHuMCP-3/CCL7; C-C motif chemokine 7; MCP3; SCYA6; SCYA7 ; 重组人单核细胞趋化蛋白-3/CCL7 (CHO表达) Species HumanSource CHO Accession P80098 Gene ID 6354 Molecular Weight 10-18 kDa AA Sequence QPVGINTSTT CCYRFINKKI PKQRLESYRR TTSSHCPREA VIFKTKLDKE ICADPTQKWV QDFMKHLDKK TQTPKL Biological Activity The ED50 is <1.5 μg/mL as measured by CHO-K1/Gα15/hCCR1 cells (human Gα15 and human CCR1 stably expressed in CHO-K1 cells). Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against PBS. Endotoxin Level <0.2 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Human Monocyte Chemotactic Protein-3/CCL7 (CHO-expressed) (rHuMCP-3/CCL7) to 100 μg/mL using ddH2O or PBS. Storage & Stability Lyophilized recombinant Human Monocyte Chemotactic Protein-3/CCL7 (CHO-expressed) (rHuMCP-3/CCL7) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background CCL7 is a chemotactic factor and attractant for various kinds of leukocytes, including monocytes and neutrophils. CCL7 is widely expressed in multiple cell types and can participate in anti-inflammatory responses through binding to its receptors to mediate the recruitment of immune cells. Abnormal CCL7 expression is associated with certain immune diseases. CCL7 alsoplays a pivotal role in tumorigenesis[1]. |