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Recombinant Human Platelet factor-4/CXCL4 (HEK293-expressed)

英文名：
Cas号：
检测信息查询
货号 规格 货期 库存 价格 会员价 订购
1308132792-10 μg 0 ￥3200 请登录
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1308132792-50 μg 0 ￥7800 请登录
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别 名
Cas号
M D L
分子式
分子量
产品参数
性状 Recombinant Human Platelet factor-4/CXCL4 (HEK293-expressed) 是 CXC 趋化因子家族成员，具有抗肝素、抗血管生成的活性，同时可抑制肿瘤新生血管形成。
Synonyms
rHuPF-4/CXCL4; C-X-C motif chemokine 4; Oncostatin A; SCYB4 ; 重组人血小板因子-4/CXCL4 (HEK293 细胞表达)
Species
Human

Source
HEK 293

Accession
P02776

Gene ID
5196

Molecular Weight
Approximately 7.8 kDa

AA Sequence
EAEEDGDLQC LCVKTTSQVR PRHITSLEVI KAGPHCPTAQ LIATLKNGRK ICLDLQAPLY KKIIKKLLES

Biological Activity
The ED50 is <10 μg/mL as measured by its ability to inhibit human FGF-basic-dependent proliferation of NR6R 3T3 mouse fibroblast cells.

Appearance
Lyophilized powder.

Formulation
Lyophilized after extensive dialysis against PBS.

Endotoxin Level
<0.2 EU/μg, determined by LAL method.

Reconstitution
Reconstitute the lyophilized recombinant Human Platelet factor-4/CXCL4 (HEK293-expressed) (rHuPF-4/CXCL4) to 100 μg/mL using ddH2O or PBS.

Storage & Stability
Lyophilized recombinant Human Platelet factor-4/CXCL4 (HEK293-expressed) (rHuPF-4/CXCL4) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping
Room temperature in continental US; may vary elsewhere.

Background
PF-4/CXCL4 is a member of the CXC chemokine family produced by cells of the megakaryocytic lineage. CXCL4 has antiheparin activity, responsible for the important role of CXCL4 in the regulation of coagulation processes. CXCL4 has exhibits antiangiogenic properties in vitro and in vivo and inhibits tumor neovascularization through a variety of mechanisms[1].
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