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Recombinant Human VEGF-D (HEK293-expressed)

英文名：
Cas号：
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别 名
Cas号
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分子式
分子量
产品参数
性状 Recombinant Human VEGF-D (HEK293-expressed) 是一种促进血管再生和淋巴再生的调节因子。
Synonyms
rHuVEGF-D; Vascular endothelial growth factor D; FIGF ; 重组人源血管内皮生长因子D (HEK293-expressed)
Species
Human

Source
CHO

Accession
O43915

Gene ID
2277

Molecular Weight
18-19 kDa

AA Sequence
FAATFYDIET LKVIDEEWQR TQCSPRETCV EVASELGKST NTFFKPPCVN VFRCGGCCNE ESLICMNTST SYISKQLFEI SVPLTSVPEL VPVKVANHTG CKCLPTAPRH PYSIIRR

Biological Activity
The ED50 is <1 μg/mL as measured by HUVEC cells.

Appearance
Lyophilized powder.

Formulation
Lyophilized after extensive dialysis against PBS.

Endotoxin Level
<0.2 EU/μg, determined by LAL method.

Reconstitution
Reconstitute the lyophilized recombinant Human VEGF-D (HEK293-expressed) (rHuVEGF-D) to 100 μg/mL using ddH2O or PBS.

Storage & Stability
Lyophilized recombinant Human VEGF-D (HEK293-expressed) (rHuVEGF-D) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping
Room temperature in continental US; may vary elsewhere.

Background
VEGF-D, a powerful lymphangiogenic and angiogenic growth factor, is also a major regulator of chylomicron metabolism in mice[1]. Vascular endothelial growth factor D (VEGF-D) has important functions in lymphangiogenesis and angiogenesis. High plasma levels of VEGF-D have been associated with incidence of heart failure. The association of VEGF-D with atrial fibrillation (AF) and stroke is unclear and we hypothesised that VEGF-D could also be associated with incidence of AF and ischaemic stroke[2].
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