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Recombinant Human Betacellulin (HEK293-expressed)

英文名：
Cas号：
检测信息查询
货号 规格 货期 库存 价格 会员价 订购
1308132841-10 μg 0 ￥3200 请登录
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1308132841-50 μg 0 ￥8400 请登录
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别 名
Cas号
M D L
分子式
分子量
产品参数
性状 Recombinant Human Betacellulin (HEK293-expressed) 是 HEK293 细胞中产生的一种糖蛋白，能够通过提高来自导管和胰腺腺泡细胞的 β 细胞的分化和再生来提高葡萄糖耐受性。
Synonyms
rHuBetacellulin; BTC
Species
Human

Source
HEK 293

Accession
P35070

Gene ID
685

Molecular Weight
15-18 kDa

AA Sequence
DGNSTRSPET NGLLCGDPEE NCAATTTQSK RKGHFSRCPK QYKHYCIKGR CRFVVAEQTP SCVCDEGYIG ARCERVDLFY

Biological Activity
The ED50 is <4 pg/mL as measured by 3T3 cells.

Appearance
Lyophilized powder.

Formulation
Lyophilized after extensive dialysis against PBS.

Endotoxin Level
<0.2 EU/μg, determined by LAL method.

Reconstitution
Reconstitute the lyophilized recombinant Human Betacellulin (HEK293-expressed) (rHuBetacellulin) to 100 µg/mL using ddH2O or diluted with PBS.

Storage & Stability
Lyophilized recombinant Human Betacellulin (HEK293-expressed) (rHuBetacellulin) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping
Room temperature in continental US; may vary elsewhere.

Background
Betacellulin (BTC), a member of the epidermal growth factor family, is expressed predominantly in the human pancreas and induces the differentiation of a pancreatic acinar cell line (AR42J) into insulin-secreting cells. Betacellulin binds and activates the EGF receptor (EGFR/erbB-1) and erbB-4, and it induces tyrosine phosphorylation of erbB-2, which couples with the EGFR or erbB-4[1].
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