Recombinant Human Interleukin-17A, His (CHO-expressed)

英文名:
Cas号:
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1308132885-50 μg 0 ¥7200 请登录
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别 名
Cas号
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分子式
分子量
产品参数
性状 Recombinant Human Interleukin-17A, His (CHO-expressed) 是一种细胞因子,在先天免疫和后天免疫中发挥重要作用。
Synonyms
rHuIL-17A, His; CTLA-8; IL-17A ; 重组人白介素-17A (CHO 细胞表达)
Species
Human

Source
CHO

Accession
Q16552

Gene ID
3605

Molecular Weight
14-22 kDa

AA Sequence
GITIPRNPGC PNSEDKNFPR TVMVNLNIHN RNTNTNPKRS SDYYNRSTSP WNLHRNEDPE RYPSVIWEAK CRHLGCINAD GNVDYHMNSV PIQQEILVLR REPPHCPNSF RLEKILVSVG CTCVTPIVHH VAHHHHHH

Biological Activity
The ED50 is <10 ng/mL as measured by NHDF cells, corresponding to a specific activity of >1 × 105 units/mg.

Appearance
Lyophilized powder.

Formulation
Lyophilized after extensive dialysis against PBS.

Endotoxin Level
<0.2 EU/μg, determined by LAL method.

Reconstitution
Reconstitute the lyophilized recombinant Human Interleukin-17A, His (CHO-expressed) (rHuIL-17A, His) to 100 µg/mL using ddH2O or diluted with PBS.

Storage & Stability
Lyophilized recombinant Human Interleukin-17A, His (CHO-expressed) (rHuIL-17A, His) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping
Room temperature in continental US; may vary elsewhere.

Background
IL-17A plays important roles in both innate and acquired immunity and is, especially, involved in the accumulation of polymorphonuclear neutrophil leukocytes. IL-17A mediates crucial crosstalk between the immune system and various epithelial tissues, initiating a series of defensive mechanisms against bacterial and fungal infections[1].
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