|
|
|
| 生化科研试剂 >> 抗体产品 >> 一抗 |
| |
Caldesmon Phospho (pT753) (CALD1)
Rabbit Monoclonal Antibody |
| 别 名： |
CALD1 antibody, CDM antibody, H-CAD antibody, HCAD antibody, L-CAD antibody, LCAD antibody, MGC21352 antibody, NAG22 antibody, Caldesmon antibody, antibody |
| 货号 |
品名 |
规格 |
包装 |
单价 |
货期 |
库存 |
| 1227177588 |
Caldesmon Phospho (pT753) (CALD1) |
|
100ul |
询价 |
现货 |
3天 |
| 提示信息：偏远地区如新疆西藏宁夏甘肃等地可能无法运送液体，下单前请联系客服。 |
| 性 状： |
【反应特异性】Human
【克隆 ID】EPR2211Y
【用途】WB , ICC
【抗原分子量】120-150 (smooth muscle)/70-80
|
| 质量标准： |
【产品介绍】Caldesmon is a smooth muscle and
nonmuscle regulatory protein that interacts with
actin, myosin, tropomyosin, and calmodulin (1,2).
Smooth muscle caldesmon is an elongated molecule with
a calmodulin, tropomyosin, and actin-binding region at
the C-terminus and a myosin-binding domain at the
N-terminus (3). Caldesmon stimulates actin binding
of tropomyosin which increases the stabilization of
actin filament structure. In muscle tissues,
caldesmon inhibits the actomyosin ATPase by binding
to F-actin. This inhibition is reduced by
calcium-calmodulin and is promoted by tropomyosin
(4). Phosphorylation of non-muscle caldesmon has been
linked to reduction of caldesmon's binding properties
to actin, myosin, and calmodulin. Also,
caldesmon's inhibition of actomyosin ATPase is reduced
with its Phosphorylation (5).
Recommended Applications
WB, ICC
Applications and Recommended Dilution Factors WB: 1:1000 - 5000
ICC: 1:50 - 100
Species Reactivity Human Products Data Western blot analysis on HeLa cell lysates
using anti-Phospho-Caldesmon (pT753) RabMAb
(cat. # 2394-1), 1:5000 dilution. Cells were
either (A) untreated (B) treated with Calyculin A. |
|
沪公网安备 31012002003054号
