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Caspase-3 (active) DyLight® 488 (CASP3)
英文名：Rabbit Monoclonal Antibody
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检测信息查询
| 货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
| 1308113401-100ul | 5天 | 0 | ￥3000 | 请登录 |
| 别 名 | CASP3 antibody, CPP32 antibody, CPP32B antibody, SCA-1 antibody, Caspase-3 subunit p12 antibody, Protein Yama antibody, SREBP cleavage activity 1 antibody |
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| 产品参数 | 【产品介绍】Caspases are a family of cytosolic
aspartate-specific cysteine proteases involved in the initiation and execution of apoptosis. Caspase-3 (apopain, SCA-1, Yama and CPP32) is a member of the apoptosis execution functional group of caspases, and is either partially or totally responsible for the proteolytic cleavage of many key proteins during apoptosis, such as poly (ADP-ribose) polymerase (PARP) (1,2,3). Caspase-3 is a cytosolic protein found in cells as an inactive 32 kDa proenzyme. It is activated by proteolytic cleavage into two active subunits only when cells undergo apoptosis (3). Recommended Applications ICC Applications and Recommended Dilution Factors ICC: 1:50 - 100 Species Reactivity Human Products Data Immunofluorescent staining of HeLa without treatment (left) and HeLa treated with Staurosporine (right) cells using anti-Caspase-3 (active) antibody conjugated with Dylight 488 (green, Cat# 4590-1) and Dapi (blue). Specificity A synthetic peptide corresponding to residues following Ser29 of human caspase-3 (N-terminus of p17 subunit) was used as immunogen. This antibody only detects the active form of caspase-3 (p17 subunit). |
| 性状 | 【反应特异性】Human
【克隆 ID】E83-77 【用途】ICC 【抗原分子量】17kDa |
| 贮存 | Storage Condition and Buffer Store at 2-8° C. PBS (pH 7.2), 0.02% sodium azide, 0.05% BSA. Protect from light. Stable for 6 months from date of receipt. |
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