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DLC8 (N-term)
英文名：Rabbit Monoclonal IgG
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检测信息查询
| 货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
| 1308113513-100ul | 现货 | 0 | ￥0 | 请登录 |
| 别 名 | Dynein light chain LC8-type 1, 8 kDa dynein light chain, DLC8, Protein inhibit o r of neuronal nitric oxide synthase, PIN |
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| 产品参数 | 【产品介绍】DLC8 protein bound efficiently to gephyrin in
in vitro binding assays a n d colocalized with gephyrin during coexpression in HEK293 cells. The binding site f o r DLC8 was mapped to a fragment of 63 amino acids within the central linker domain of gephyrin. In hippocampal neurons, endogenous DLC8 protein was enriched at synaptic sites identified by synaptophysin a n d gephyrin immunostaining. Because DLC8 has been described as stoichiometric components of cytoplasmic dynein a n d myosin-Va complexes, results suggest that mot o r proteins are involved in the subcellular localization of gephyrin (1). DLC8 was identified as a transp o r t molecule in the cytoplasm. DLC8 co-localizes with TRPS1 in dot-like structures in the cell nucleus. In an electroph o r etic mobility shift assay it was shown that the interaction of DLC8 a n d TRPS1 lowers the binding of TRPS1 to the GATA consensus sequence. In addition DLC8 is able to suppress the transcriptional repression activity of TRPS1 (2). WB: 1:10,000 IHC: 1:100 250 ICC: 1:100 250 IP: 1:100 A. Western blot analysis on HeLa cell lysate using anti-DLC8 RabMAb (cat. # 2003-1), dilution 1:10,000. B. Immunohistochemical staining of paraffin-embedded human liver using anti-DLC8 RabMAb (cat. #2003-1). |
| 性状 | 【反应特异性】Human , Mouse , Rat
【克隆 ID】EP1660Y 【用途】WB , IHC , ICC , IP 【抗原分子量】10 kDa |
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