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DNA-PK/PRKDC Phospho (pS2056)
英文名：Rabbit Monoclonal Antibody
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检测信息查询
| 货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
| 1308113517-100ul | 现货 | 0 | ￥0 | 请登录 |
| 别 名 | PRKDC antibody, DNA-PKcs antibody, DNAPK antibody, DNPK1 antibody, HYRC antibody, HYRC1 antibody, XRCC7 antibody, p350 antibody, DNA-dependent protein kinase catalytic subunit antibody, DNPK1 antibody, p460 antibody |
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| 产品参数 | 【产品介绍】DNA-activated serine/threonine protein
kinase (DNA-PK) is a nuclear protein kinase that is involved in DNA nonhomologous end joining (NHEJ) required for double- strand brake repair and V(D)J recombination. DNA-PK is composed of a large catalytic subunit of ~470 kDa (DNA-PKcs) and a DNA binding heterodimer of approximately 70- and 80-kDa subunits called Ku. (1-2). Autophosphorylation of DNA-PK correlates with loss of protein kinase activity and dissociation of the DNA-PKcs-Ku complex. DNA-PK phosphorylates Hsp90, p53 and c-Jun (3-4). Recommended Applications WB, IHC Applications and Recommended Dilution Factors WB: 1:1,000 - 10,000 IHC: 1:100 - 250 Species Reactivity * Human *Species cross-reactivity is based on WB analysis Products Data Immunohistochemical analysis of paraffin-embedded human brain tissue using anti-Phospho-DNA-PK/PRKDC (pS2056) RabMAb (cat. #3892-1). Western blot analysis on Jurkat cell lysates using anti-Phospho-DNA-PK/PRKDC (pS2056) RabMAb (cat. #3892-1). Cells were either (A) untreated (B) treated with Alkaline Phosphatase. Specificity A phospho specific peptide corresponding to residues surrounding Serine 2056 of human DNA-PK/PRKDC was used as an immunogen. This antibody only detects DNA-PK/PRKDC phosphorylated at Serine 2056. |
| 性状 | 【反应特异性】Human
【克隆 ID】EPR5670 【用途】WB , IHC 【抗原分子量】460kDa |
| 贮存 | Storage Condition and Buffer Store at -20° C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
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