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Recombinant Mouse Interleukin-33

英文名：
Cas号：
检测信息查询
货号 规格 货期 库存 价格 会员价 订购
1308132731-10 μg 0 ￥4600 请登录
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1308132731-50 μg 0 ￥14800 请登录
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别 名
Cas号
M D L
分子式
分子量
产品参数
性状 Recombinant Mouse Interleukin-33是来自IL-1家族的组织来源的核细胞因子， 在稳态和炎症期间，均可在内环细胞，上皮细胞和成纤维细胞样细胞中大量表达。
Synonyms
rMuIL-33; Il33 ; 重组小鼠白细胞介素-33
Species
Mouse

Source
E. coli

Accession
Q8BVZ5

Gene ID
77125

Molecular Weight
Approximately 17.5 kDa

AA Sequence
SIQGTSLLTQ SPASLSTYND QSVSFVLENG CYVINVDDSG KDQEQDQVLL RYYESPCPAS QSGDGVDGKK LMVNMSPIKD TDIWLHANDK DYSVELQRGD VSPPEQAFFV LHKKSSDFVS FECKNLPGTY IGVKDNQLAL VEEKDESCNN IMFKLSKI

Biological Activity
The ED50 is <0.5 ng/mL as measured by murine D10S cells, corresponding to a specific activity of >2.0 × 106 units/mg.

Appearance
Lyophilized powder.

Formulation
Lyophilized after extensive dialysis against PBS, and 1 mM EDTA.

Endotoxin Level
<1 EU/μg, determined by LAL method.

Reconstitution
Reconstitute the lyophilized recombinant Mouse Interleukin-33 (rMuIL-33) to 0.1-1.0 mg/mL using sterile distilled water or aqueous buffer containing 0.1% BSA.

Storage & Stability
Lyophilized recombinant Mouse Interleukin-33 (rMuIL-33) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping
Room temperature in continental US; may vary elsewhere.

Background
Interleukin-33 (IL-33) was originally described as an inducer of type 2 immune responses, activating T helper 2 cells and mast cells. Evidence shows that IL-33 also potently stimulates group 2 innate lymphoid cells, regulatory T cells, TH1 cells, CD8+ T cells and natural killer cells[1]. IL-33 is a crucial immune modulator with pleiotropic activities in type-2, type-1 and regulatory immune responses, and important roles in allergic, fibrotic, infectious, and chronic inflammatory diseases[2].
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