Recombinant Mouse Macrophage Inflammatory Protein-2/CXCL2

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Cas号:
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1308132767-10 μg 0 ¥4800 请登录
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1308132767-50 μg 0 ¥11800 请登录
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别 名
Cas号
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分子式
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产品参数
性状 Recombinant Mouse Macrophage Inflammatory Protein-2/CXCL2 是一种 CXC 趋化因子,能够将中性粒细胞招募到感染部位。
Synonyms
rMuMIP-2/CXCL2; C-X-C motif chemokine 2; SCYB2 ; 重组小鼠巨噬细胞炎性蛋白-2/CXCL2
Species
Mouse

Source
E. coli

Accession
P10889

Gene ID
20310

Molecular Weight
Approximately 8.0 kDa

AA Sequence
GAVVASELRC QCLKTLPRVD FKNIQSLSVT PPGPHCAQTE VIATLKGGQK VCLDPEAPLV QKIIQKILNK GKAN

Biological Activity
The EC50 is <1 ng/mL as measured by CHO-K1/Gα15/mCXCR2 cells (human Gα15 and mouse CXCR2 stably expressed in CHO-K1 cells).

Appearance
Lyophilized powder.

Formulation
Lyophilized after extensive dialysis against PBS.

Endotoxin Level
<0.2 EU/μg, determined by LAL method.

Reconstitution
Reconstitute the lyophilized recombinant Mouse Macrophage Inflammatory Protein-2/CXCL2 (rMuMIP-2/CXCL2) to 100 μg/mL using ddH2O or PBS.

Storage & Stability
Lyophilized recombinant Mouse Macrophage Inflammatory Protein-2/CXCL2 (rMuMIP-2/CXCL2) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping
Room temperature in continental US; may vary elsewhere.

Background
MIP-2, a member of the CXC chemokine family, is a peptide derived from monocytes/macrophages, and can recruit neutrophils to infection sites. MIP-2 release has an important impact on the development of early immune responses. MIP-2 is mainly produced by macrophages, one of the most dominant and widely distributed inflammatory cells, and is involved in the initiation and maintenance of the acute inflammatory response[1].
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