本网站销售的所有产品仅用于工业应用或者科学研究等非医疗目的，不可用于人类或动物的临床诊断或者治疗，非药用，非食用。
Recombinant Human Twisted Gastrulation, His
| 别 名 | |
| Cas号 | |
| M D L | |
| 分子式 | |
| 分子量 | |
| 产品参数 | |
| 性状 | Recombinant Human Twisted Gastrulation, His 是带有标签的人重组 Twisted gastrulation。Recombinant Human Twisted Gastrulation 对预激活 T 细胞 (包括 IL-2、IL-4、IFN-γ 和 IL-10) 的 CD3 介导的增殖和细胞因子产生具有有效的抑制作用
Synonyms rHuTwisted Gastrulation, His; TWSG1 ; 重组人扭曲原肠形成，His 标签 Species Human Source HEK 293 Accession Q9GZX9 Gene ID 57045 Molecular Weight 30-33 kDa AA Sequence HHHHHHHHCN KALCASDVSK CLIQELCQCR PGEGNCSCCK ECMLCLGALW DECCDCVGMC NPRNYSDTPP TSKSTVEELH EPIPSLFRAL TEGDTQLNWN IVSFPVAEEL SHHENLVSFL ETVNQPHHQN VSVPSNNVHA PYSSDKEHMC TVVYFDDCMS IHQCKISCES MGASKYRWFH NACCECIGPE CIDYGSKTVK CMNCMF Biological Activity The ED50 is <2 μg/mL as measured by ATDC-5 chondrogenic cells. Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against PBS. Endotoxin Level <0.2 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Human Twisted Gastrulation, His (rHuTwisted Gastrulation, His) to 100 µg/mL using ddH2O or diluted with PBS. Storage & Stability Lyophilized recombinant Human Twisted Gastrulation, His (rHuTwisted Gastrulation, His) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background Twisted gastrulation (TSG) is one of the genes regulated by Tob and acts as an inhibitor of activated mature CD4+ human T lymphocytes. Recombinant Tsg had a potent inhibitory effect on CD3-mediated proliferation and cytokine production of preactivated T cells, including IL-2, IL-4, IFN-γ, and IL-10. Tsg is a potent agonist of TGF-β downstream signaling in activated human CD4+ T cells and suggest that enhancement of TGF-β mediating signaling by Tsg may represent a novel target for molecular intervention for control of aberrant T-cell responses during ongoing graft-versus-host disease (GVHD) and autoimmune diseases[1]. |
| 贮存 |
- Recombinant Human TIGIT, Fc Chimera (HEK293-expressed)
- Recombinant Human T Cell Immunoglobulin Mucin 3, Fc Chimera (HEK293-expressed)
- Recombinant Human Tumor Necrosis Factor alpha, His
- Recombinant Mouse Tumor Necrosis Factor alpha, His
- Recombinant Human Twisted Gastrulation, His
- 乙二胺二邻羟苯基大乙酸铁钠 16455-61-1
- Recombinant Human Vaspin
- Recombinant Human VEGF-121
- Recombinant Mouse VEGF164 (P.pastoris-expressed)
沪公网安备 31012002003054号