c-Myb (MYB)

英文名:Rabbit Monoclonal Antibody
Cas号:
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别 名 MYB antibody, Cmyb antibody, c-myb antibody, c-myb_CDS antibody, efg antibody, Transcriptional activator Myb antibody, Proto-oncogene c-Myb antibody
Cas号
M D L
分子式
分子量
产品参数 【产品介绍】The c-Myb proto-oncogene is a 75 kDa
protein involved in growth regulation and differentiation
in many different cell types but it is
predominantly expressed in immature hematopoietic
cells where it plays an important role in
cell proliferation. c-Myb activity is directly regulated
by cyclin D1 and CDKs and it is believed that c-Myb
activity is regulated during the cell cycle in
hematopoietic cells (2). Disrupting c-myb function
might, therefore, prove an effective therapeutic
strategy for controlling leukemic cell growth (3).
c-Myb binds to promoter sequences of genes such as c-Myc
or Bcl-2 that are expressed in cutaneous T-cell lymphoma.


Recommended Applications

WB, IHC, ICC, IP
Applications and Recommended Dilution Factors

WB: 1:10,000
IHC: 1:100 - 250
ICC: 1:100 - 250
IP: 1:50
Species Reactivity *

Human

*Cross reactivity determined by western blot only.


Products Data


A. Western blot analysis on Ramos membrane using
anti-c-Myb RabMAb (cat. # 1792-1), dilution 1:10,000

B. Immunohistochemical staining of paraffin-embedded
human cervical carcinoma using anti-c-Myb RabMAb
(cat. # 1792-1).

Specificity

A synthetic peptide corresponding to residues near
the N-terminus of human c-myb was used as an immunogen.
性状 【反应特异性】Human
【克隆 ID】EP769Y
【用途】WB , IHC , ICC , IP
【抗原分子量】75/77kDa
贮存 Storage Condition and Buffer Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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