COMT antibody

英文名:Rabbit Monoclonal Antibody
Cas号:
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别 名 COMT, - antibody, Catechol O-methyltransferase antibody, antibody
Cas号
M D L
分子式
分子量
产品参数 【产品介绍】Catechol-O-methyltransferase catalyzes
the transfer of a methyl group from S-adenosylmethionine
to catecholamines, including the neurotransmitters
dopamine, epinephrine, and norepinephrine.
This O-methylation results in one of the major
degradative pathways of the catecholamine transmitters.
In addition to its role in the metabolism of
endogenous substances, COMT is important in the
metabolism of catechol drugs used in the treatment
of hypertension, asthma, and Parkinson's disease.
COMT is found in two forms in tissues, a soluble
form (S-COMT) and a membrane-bound form (MB-COMT).
The differences between S-COMT and MB-COMT reside within
the N-termini (1).


Recommended Applications

WB, FC
Applications and Recommended Dilution Factors

WB: 1:1,000 - 10,000
FC: 1:10 - 100
Species Reactivity *

Human, Rat

*Species cross-reactivity is based on WB analysis.


Products Data

Western blot analysis on (A) fetal liver, (B) A431,
and (C) Molt-4 lysates using anti-COMT RabMAb (cat. #5126-1).

Flow cytometric analysis of A431 cells using
anti-COMT RabMAb (red) (cat.# 5126-1) or a rabbit
IgG (negative) (green).

Specificity

A synthetic peptide corresponding to residues in human
COMT was used as an immunogen.
性状 【反应特异性】Human , Rat
【克隆 ID】EPR6491(B)
【用途】WB , FC
【抗原分子量】24-30kDa
贮存 Storage Condition and Buffer Store at -20 °C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt
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