COX1 / Cyclooxygenase 1 (PTGS1)

英文名:Rabbit Monoclonal Antibody
Cas号:
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1308113461-100ul 现货 0 ¥0 请登录
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别 名 PTGS1 antibody, COX1 antibody, COX3 antibody, PCOX1 antibody, PGG/HS antibody, PGHS-1 antibody, PGHS1 antibody, PHS1 antibody, PTGHS antibody, Prostaglandin G/H synthase 1 antibody, Prostaglandin-endoperoxide synthase 1 antibody
Cas号
M D L
分子式
分子量
产品参数 【产品介绍】COX1 / Cyclooxygenase 1, also known
as Prostaglandin-endoperoxide synthase (PTGS), is the
key enzyme in prostaglandin biosynthesis and acts both as
a dioxygenase and as a peroxidase. There are two isozymes
of COX1 / Cyclooxygenase 1: a constitutive COX1 and
an inducible COX2, which differ in their regulation
of expression and tissue distribution. COX1 /
Cyclooxygenase 1 regulates angiogenesis in endothelial
cells and is inhibited by nonsteroidal
anti-inflammatory drugs such as aspirin. It is thought to
be involved in cell-cell signaling and maintaining
tissue homeostasis (1).


Recommended Applications

WB, IHC
Applications and Recommended Dilution Factors

WB: 1:1,000 - 10,000
IHC: 1:50 - 100
Species Reactivity *

Human, Mouse, Rat

*Species cross-reactivity is based on WB analysis.

Products Data

Western blot analysis on (A) C2C12, (B) A431,
(C) NIH/3T3, (D) Neuro-2a, and (E) L6 cell lysates
using anti-COX1 / Cyclooxygenase 1 RabMAb (cat. #5153-1).

Immunohistochemical analysis of paraffin-embedded
human stomach tissue using anti-COX1 / Cyclooxygenase
1 RabMAb (cat. #5153-1).

Specificity

A synthetic peptide corresponding to residues in human
COX1 / Cyclooxygenase 1 was used as an immunogen.
性状 【反应特异性】Human , Mouse , Rat
【克隆 ID】EPR5867
【用途】WB , IHC
【抗原分子量】65 - 70kDa
贮存 Storage Condition and Buffer Store at -20 °C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt
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